King Ferdinand the Catholic made a donation for the construction of this church. The architects were Juan de Orozco (church), Martín de Villarreal (facade) and Juan de Badajoz (cloister and sacristy).
The facade is one of the most outstanding of the Spanish Renaissance (plateresque style). It consists of one single piece with walls divided into two areas, decorated with openwork crests and pillars. The plinth contains medallions with Greek and Latin figures and others from Spanish history. The area above the plinth is decorated with angels’ heads.
It has the longest Plateresque (Spanish Renaissance) façade in Spain. It is a single stretch of wall on two levels, topped out with pierced cresting and candelabra. The lower storey is decorated with medallions of Graeco-Lating and Spanish historical personages, and the upper one is adorned with heads of angels.